Linker Information
General Information of This Linker
| Linker ID |
LIN0TIJGC
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|---|---|---|---|---|---|---|
| Linker Name |
C4-VC-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C22H34N6O6
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| Isosmiles |
CC([C@H](NC(CCC(N)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)C
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| InChI |
InChI=1S/C22H34N6O6/c1-13(2)19(28-18(31)10-9-17(23)30)21(33)27-16(4-3-11-25-22(24)34)20(32)26-15-7-5-14(12-29)6-8-15/h5-8,13,16,19,29H,3-4,9-12H2,1-2H3,(H2,23,30)(H,26,32)(H,27,33)(H,28,31)(H3,24,25,34)/t16-,19-/m0/s1
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| InChIKey |
QBJVJBQWNXLSKE-LPHOPBHVSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
478.55
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Polar area
|
205.74
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Complexity
|
814.0992132
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xlogp Value
|
-0.543
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Heavy Count
|
34
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Rot Bonds
|
14
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Hbond acc
|
6
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker