Linker Information
General Information of This Linker
| Linker ID |
LIN0TGRYG
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
B-9 Linker
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C31H46N6O10
|
|||||
| Isosmiles |
CC([C@H](NC(CCOCCOCCOCCN1C(C=C(C)C1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(O)C=C2)=O)=O)C
|
|||||
| InChI |
InChI=1S/C31H46N6O10/c1-20(2)27(29(42)35-24(5-4-11-33-31(32)44)28(41)34-22-6-8-23(38)9-7-22)36-25(39)10-13-45-15-17-47-18-16-46-14-12-37-26(40)19-21(3)30(37)43/h6-9,19-20,24,27,38H,4-5,10-18H2,1-3H3,(H,34,41)(H,35,42)(H,36,39)(H3,32,33,44)/t24-,27-/m0/s1
|
|||||
| InChIKey |
WZLBJNCGWGLRPU-IGKIAQTJSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
662.741
|
Polar area
|
227.72
|
||
|
Complexity
|
1194.929983
|
xlogp Value
|
0.1598
|
|||
|
Heavy Count
|
47
|
Rot Bonds
|
22
|
|||
|
Hbond acc
|
10
|
Hbond Donor
|
6
|
|||
Each Antibody-drug Conjugate Related to This Linker