Linker Information
General Information of This Linker
| Linker ID |
LIN0TCTNV
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|---|---|---|---|---|---|---|
| Linker Name |
DBCO-GGG
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H28N4O6
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| Isosmiles |
O=C(NCC(O)=O)CNC(CNC(CCCCC(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)=O)=O)=O
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| InChI |
InChI=1S/C27H28N4O6/c32-23(28-15-24(33)29-16-25(34)30-17-27(36)37)11-5-6-12-26(35)31-18-21-9-2-1-7-19(21)13-14-20-8-3-4-10-22(20)31/h1-4,7-10H,5-6,11-12,15-18H2,(H,28,32)(H,29,33)(H,30,34)(H,36,37)
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| InChIKey |
NQLOKXZJULGNNO-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
504.543
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Polar area
|
144.91
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Complexity
|
1205.839689
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xlogp Value
|
0.9266
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Heavy Count
|
37
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Rot Bonds
|
11
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Hbond acc
|
5
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker