Linker Information
General Information of This Linker
| Linker ID |
LIN0TCBYG
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|---|---|---|---|---|---|---|
| Linker Name |
IG-L-24 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H32N6O7
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| Isosmiles |
C[C@H](NC(CNC(CCN1C(C=CC1=O)=O)=O)=O)C(NC2=CC=C(C=C2)COC(N(C)CCNC)=O)=O
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| InChI |
InChI=1S/C24H32N6O7/c1-16(27-20(32)14-26-19(31)10-12-30-21(33)8-9-22(30)34)23(35)28-18-6-4-17(5-7-18)15-37-24(36)29(3)13-11-25-2/h4-9,16,25H,10-15H2,1-3H3,(H,26,31)(H,27,32)(H,28,35)/t16-/m0/s1
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| InChIKey |
YGQXFTVOLHWZTA-INIZCTEOSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
516.555
|
Polar area
|
166.25
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Complexity
|
974.9788377
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xlogp Value
|
-0.6511
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Heavy Count
|
37
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Rot Bonds
|
13
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Hbond acc
|
8
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker