Linker Information
General Information of This Linker
| Linker ID |
LIN0SXNGS
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| Linker Name |
Linker of ADC2-32
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C35H47N7O14
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| Isosmiles |
O=C(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)[C@H](CCC(NC(O2)[C@H](O)[C@H](O)[C@H]2CO)=O)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C35H47N7O14/c43-19-23-31(52)32(53)35(56-23)41-25(45)11-10-21(39-24(44)9-5-2-6-14-42-28(48)12-13-29(42)49)33(54)37-16-26(46)36-17-27(47)40-22(34(55)38-18-30(50)51)15-20-7-3-1-4-8-20/h1,3-4,7-8,12-13,21-23,31-32,35,43,52-53H,2,5-6,9-11,14-19H2,(H,36,46)(H,37,54)(H,38,55)(H,39,44)(H,40,47)(H,41,45)(H,50,51)/t21-,22-,23+,31+,32+,35?/m0/s1
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| InChIKey |
FWGLVXLSXDRVMA-SXDINHEASA-N
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| Pharmaceutical Properties |
Molecule Weight
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789.796
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Polar area
|
319.2
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Complexity
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1533.526815
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xlogp Value
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-4.5473
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Heavy Count
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56
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Rot Bonds
|
23
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Hbond acc
|
13
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Hbond Donor
|
10
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Each Antibody-drug Conjugate Related to This Linker