Linker Information
General Information of This Linker
| Linker ID |
LIN0SVKCU
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| Linker Name |
TW202506738A-C-043-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C17H20N4O4
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| Isosmiles |
CC1=CC=C(NC([C@@H](NC(C(N2C(C=CC2=O)=O)CN)=O)C)=O)C=C1
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| InChI |
InChI=1S/C17H20N4O4/c1-10-3-5-12(6-4-10)20-16(24)11(2)19-17(25)13(9-18)21-14(22)7-8-15(21)23/h3-8,11,13H,9,18H2,1-2H3,(H,19,25)(H,20,24)/t11-,13?/m0/s1
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| InChIKey |
HDERCMSGROJDJA-AMGKYWFPSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
344.371
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Polar area
|
121.6
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Complexity
|
678.0587879
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xlogp Value
|
-0.30948
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Heavy Count
|
25
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Rot Bonds
|
6
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Hbond acc
|
5
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker