Linker Information
General Information of This Linker
| Linker ID |
LIN0SRSEO
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| Linker Name |
BrAc-Ala-Glu
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C10H15BrN2O6
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| Isosmiles |
O=C(N[C@H](C(O)=O)CCC(O)=O)[C@@H](C)NC(CBr)=O
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| InChI |
InChI=1S/C10H15BrN2O6/c1-5(12-7(14)4-11)9(17)13-6(10(18)19)2-3-8(15)16/h5-6H,2-4H2,1H3,(H,12,14)(H,13,17)(H,15,16)(H,18,19)/t5-,6+/m1/s1
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| InChIKey |
FVGNPRQMGAFTBJ-RITPCOANSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
339.142
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Polar area
|
132.8
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Complexity
|
343.0498112
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xlogp Value
|
-0.6798
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Heavy Count
|
19
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Rot Bonds
|
8
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Hbond acc
|
4
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker