Linker Information
General Information of This Linker
| Linker ID |
LIN0SPZWI
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| Linker Name |
WO2024102603A1+lgG2a-Val-Cit-Pab-MMAE+Linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C48H75N5O9
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| Isosmiles |
CO[C@@H]([C@]1([H])CCCN1C(C[C@@H](OC)C(N(C([C@@H](NC(C(C(C)C)C(C(OCC2=CC=C(N)C=C2)=O)C)=O)C(C)C)=O)C)[C@H](CC)C)=O)[C@H](C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)C
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| InChI |
InChI=1S/C48H75N5O9/c1-13-30(6)42(52(10)47(58)41(29(4)5)51-46(57)40(28(2)3)31(7)48(59)62-27-34-21-23-36(49)24-22-34)38(60-11)26-39(54)53-25-17-20-37(53)44(61-12)32(8)45(56)50-33(9)43(55)35-18-15-14-16-19-35/h14-16,18-19,21-24,28-33,37-38,40-44,55H,13,17,20,25-27,49H2,1-12H3,(H,50,56)(H,51,57)/t30-,31?,32+,33+,37-,38+,40?,41-,42?,43+,44+/m0/s1
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| InChIKey |
XFGPVQWZZJHBCZ-ZYYPRULZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
866.154
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Polar area
|
189.83
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Complexity
|
1680.712406
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xlogp Value
|
5.5197
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Heavy Count
|
62
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Rot Bonds
|
23
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Hbond acc
|
10
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker