Linker Information
General Information of This Linker
| Linker ID |
LIN0SOPRF
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|---|---|---|---|---|---|---|
| Linker Name |
Coumpound7
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H56N6O14
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| Isosmiles |
COCCOCCOCCOCCN(COCC(O)=O)C(CNC([C@@H](NC(CNC(CNC(CCCCCN1C(CCC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O
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| InChI |
InChI=1S/C37H56N6O14/c1-53-16-17-55-20-21-56-19-18-54-15-14-42(27-57-26-36(50)51)35(49)25-40-37(52)29(22-28-8-4-2-5-9-28)41-32(46)24-39-31(45)23-38-30(44)10-6-3-7-13-43-33(47)11-12-34(43)48/h2,4-5,8-9,29H,3,6-7,10-27H2,1H3,(H,38,44)(H,39,45)(H,40,52)(H,41,46)(H,50,51)/t29-/m0/s1
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| InChIKey |
JJJHXAPCMHKJQN-LJAQVGFWSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
808.883
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Polar area
|
257.54
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Complexity
|
1345.619639
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xlogp Value
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-1.6446
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Heavy Count
|
57
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Rot Bonds
|
32
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Hbond acc
|
13
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker