Linker Information
General Information of This Linker
| Linker ID |
LIN0SMUSB
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|---|---|---|---|---|---|---|
| Linker Name |
DL1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C17H24N4O6
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| Isosmiles |
C[C@H](NC([C@@H](NC([C@H](CC1)CN1CCN2C(C=CC2=O)=O)=O)C)=O)C(O)=O
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| InChI |
InChI=1S/C17H24N4O6/c1-10(15(24)19-11(2)17(26)27)18-16(25)12-5-6-20(9-12)7-8-21-13(22)3-4-14(21)23/h3-4,10-12H,5-9H2,1-2H3,(H,18,25)(H,19,24)(H,26,27)/t10-,11-,12+/m0/s1
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| InChIKey |
FSPSVPGAFCIJIM-SDDRHHMPSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
380.401
|
Polar area
|
136.12
|
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Complexity
|
622.9494616
|
xlogp Value
|
-1.6727
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Heavy Count
|
27
|
Rot Bonds
|
8
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Hbond acc
|
6
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker