Linker Information
General Information of This Linker
| Linker ID |
LIN0SJPDI
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| Linker Name |
MC-Val-Cit-RG-7
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C54H82N8O17
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| Isosmiles |
O=C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(NCC2=CC=C(CCCOCCOCCOCCOCCOCCOCCOC)C=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C(C)C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C54H82N8O17/c1-39(2)49(60-46(63)12-6-5-7-22-62-47(64)19-20-48(62)65)51(67)59-44(11-8-21-56-52(55)68)50(66)58-43-17-14-41(15-18-43)38-79-53(69)57-37-42-16-13-40(36-45(42)61(3)54(70)71)10-9-23-73-26-27-75-30-31-77-34-35-78-33-32-76-29-28-74-25-24-72-4/h13-20,36,39,44,49H,5-12,21-35,37-38H2,1-4H3,(H,57,69)(H,58,66)(H,59,67)(H,60,63)(H,70,71)(H3,55,56,68)/t44-,49-/m0/s1
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| InChIKey |
SPXBTUIWZXMRSM-JUFRVMORSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1115.289
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Polar area
|
323.28
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Complexity
|
2104.818213
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xlogp Value
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3.4038
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Heavy Count
|
79
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Rot Bonds
|
43
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Hbond acc
|
16
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker