Linker Information
General Information of This Linker
| Linker ID |
LIN0SHHUK
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|---|---|---|---|---|---|---|
| Linker Name |
M-Gly-GluF
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C11H12N2O7
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| Isosmiles |
O=C(N1CC(N[C@H](C(O)=O)CCC(O)=O)=O)C=CC1=O
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| InChI |
InChI=1S/C11H12N2O7/c14-7(5-13-8(15)2-3-9(13)16)12-6(11(19)20)1-4-10(17)18/h2-3,6H,1,4-5H2,(H,12,14)(H,17,18)(H,19,20)/t6-/m0/s1
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| InChIKey |
GGKXFWQTMCOAGS-LURJTMIESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
284.224
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Polar area
|
141.08
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Complexity
|
452.2667787
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xlogp Value
|
-1.6544
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Heavy Count
|
20
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Rot Bonds
|
7
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Hbond acc
|
5
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker