Linker Information
General Information of This Linker
| Linker ID |
LIN0SGBID
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|---|---|---|---|---|---|---|
| Linker Name |
B-25 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H47N5O9
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| Isosmiles |
CC([C@H](NC(CCOCCOCCOCCC(C)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)C
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| InChI |
InChI=1S/C29H47N5O9/c1-20(2)26(34-25(37)11-14-42-16-18-43-17-15-41-13-10-21(3)36)28(39)33-24(5-4-12-31-29(30)40)27(38)32-23-8-6-22(19-35)7-9-23/h6-9,20,24,26,35H,4-5,10-19H2,1-3H3,(H,32,38)(H,33,39)(H,34,37)(H3,30,31,40)/t24-,26-/m0/s1
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| InChIKey |
RDORPUQAHQVTEM-AHWVRZQESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
609.721
|
Polar area
|
207.41
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Complexity
|
952.2573837
|
xlogp Value
|
0.6105
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Heavy Count
|
43
|
Rot Bonds
|
23
|
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Hbond acc
|
9
|
Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker