Linker Information
General Information of This Linker
| Linker ID |
LIN0SFYOK
|
|||||
|---|---|---|---|---|---|---|
| Name |
Mal-PEG24-Val-Cit-PAB
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C30H43N7O9
|
|||||
| Isosmiles |
CC([C@H](NC(CCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C=C2)CO)=O)=O)C
|
|||||
| InChI |
InChI=1S/C30H43N7O9/c1-19(2)27(36-24(40)12-16-46-17-14-32-23(39)11-15-37-25(41)9-10-26(37)42)29(44)35-22(4-3-13-33-30(31)45)28(43)34-21-7-5-20(18-38)6-8-21/h5-10,19,22,27,38H,3-4,11-18H2,1-2H3,(H,32,39)(H,34,43)(H,35,44)(H,36,40)(H3,31,33,45)/t22-,27-/m0/s1
|
|||||
| InChIKey |
YLBJXRNQDYCTMX-CUNXSJBXSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
645.714
|
Polar area
|
238.36
|
||
|
Complexity
|
1190.99279
|
xlogp Value
|
-0.9705
|
|||
|
Heavy Count
|
46
|
Rot Bonds
|
20
|
|||
|
Hbond acc
|
9
|
Hbond Donor
|
7
|
|||
Each Antibody-drug Conjugate Related to This Linker