Linker Information
General Information of This Linker
| Linker ID |
LIN0SDWDN
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| Linker Name |
CN116137818A-AbT-EXP23-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C26H34N4O11S
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| Isosmiles |
C[C@H](NC([C@H](C(C)C)NC(CCCCCN1C(C=CC1=O)=O)=O)=O)C(NC2=CC=C(COC(O)=O)C(S(=O)(O)=O)=C2)=O
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| InChI |
InChI=1S/C26H34N4O11S/c1-15(2)23(29-20(31)7-5-4-6-12-30-21(32)10-11-22(30)33)25(35)27-16(3)24(34)28-18-9-8-17(14-41-26(36)37)19(13-18)42(38,39)40/h8-11,13,15-16,23H,4-7,12,14H2,1-3H3,(H,27,35)(H,28,34)(H,29,31)(H,36,37)(H,38,39,40)/t16-,23-/m0/s1
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| InChIKey |
MZWVEKZRCNXCQE-HJPURHCSSA-N
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| Pharmaceutical Properties |
Molecule Weight
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610.642
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Polar area
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225.58
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Complexity
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1281.480571
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xlogp Value
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1.1973
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Heavy Count
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42
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Rot Bonds
|
15
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Hbond acc
|
9
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker