Linker Information
General Information of This Linker
| Linker ID |
LIN0SCSHN
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|---|---|---|---|---|---|---|
| Linker Name |
AU2023306656A1 ADC3 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H58N4O15
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| Isosmiles |
CC(C)[C@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)C(N[C@H](C(O)=O)C)=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C34H58N4O15/c1-26(2)32(33(43)36-27(3)34(44)45)37-29(40)7-10-46-12-14-48-16-18-50-20-22-52-24-25-53-23-21-51-19-17-49-15-13-47-11-8-35-28(39)6-9-38-30(41)4-5-31(38)42/h4-5,26-27,32H,6-25H2,1-3H3,(H,35,39)(H,36,43)(H,37,40)(H,44,45)/t27-,32-/m0/s1
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| InChIKey |
GITGYODHQZKNBP-UCGGBYDDSA-N
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| Pharmaceutical Properties |
Molecule Weight
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762.851
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Polar area
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235.82
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Complexity
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1025.909327
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xlogp Value
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-1.3293
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Heavy Count
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53
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Rot Bonds
|
35
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Hbond acc
|
14
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker