Linker Information
General Information of This Linker
| Linker ID |
LIN0SBYXH
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| Linker Name |
CN119630431A-ADC-65-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C36H37N5O9S2
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| Isosmiles |
O=C(N1CCOCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)=O)=O)C(SC3=CC=CC=C3)=C(SC4=CC=CC=C4)C1=O
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| InChI |
InChI=1S/C36H37N5O9S2/c42-28(37-21-29(43)38-22-30(44)40-27(34(47)39-23-31(45)46)20-24-10-4-1-5-11-24)16-18-50-19-17-41-35(48)32(51-25-12-6-2-7-13-25)33(36(41)49)52-26-14-8-3-9-15-26/h1-15,27H,16-23H2,(H,37,42)(H,38,43)(H,39,47)(H,40,44)(H,45,46)/t27-/m0/s1
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| InChIKey |
NTKAJQVENIYLMT-MHZLTWQESA-N
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| Pharmaceutical Properties |
Molecule Weight
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747.852
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Polar area
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200.31
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Complexity
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1644.703734
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xlogp Value
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1.7188
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Heavy Count
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52
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Rot Bonds
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20
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Hbond acc
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10
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Hbond Donor
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5
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Each Antibody-drug Conjugate Related to This Linker