General Information of This Linker
Linker ID
LIN0SBYLX
Linker Name
CN113286618A-ADC-3-linker
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C12H18N2O3S
Isosmiles
O=C(N1CC2CCC(C(N)=O)CC2)C(S)CC1=O
InChI
InChI=1S/C12H18N2O3S/c13-11(16)8-3-1-7(2-4-8)6-14-10(15)5-9(18)12(14)17/h7-9,18H,1-6H2,(H2,13,16)
InChIKey
WJEHMNXKTCLIRV-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
270.354
Polar area
80.47
Complexity
352.2346001
xlogp Value
0.3354
Heavy Count
18
Rot Bonds
3
Hbond acc
4
Hbond Donor
2
Each Antibody-drug Conjugate Related to This Linker