Linker Information
General Information of This Linker
| Linker ID |
LIN0SAYQO
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| Linker Name |
ADCProductionexampleNo.20Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C35H58N6O21P2
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| Isosmiles |
O=C1[C@H](CCO1)NC(C[C@H](NC(CCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)C(NCCOCCOCC(NCCCP(OP(O)(O)=O)(O)=O)=O)=O)=O
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| InChI |
InChI=1S/C35H58N6O21P2/c42-28(4-10-41-32(46)2-3-33(41)47)37-8-13-56-16-18-59-20-19-58-17-15-55-11-6-29(43)40-27(24-30(44)39-26-5-12-61-35(26)49)34(48)38-9-14-57-21-22-60-25-31(45)36-7-1-23-63(50,51)62-64(52,53)54/h2-3,26-27H,1,4-25H2,(H,36,45)(H,37,42)(H,38,48)(H,39,44)(H,40,43)(H,50,51)(H2,52,53,54)/t26-,27-/m0/s1
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| InChIKey |
BVRAQHOKXVXPFN-SVBPBHIXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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960.818
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Polar area
|
368.62
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Complexity
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1552.30376
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xlogp Value
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-3.8688
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Heavy Count
|
64
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Rot Bonds
|
37
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Hbond acc
|
18
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker