Linker Information
General Information of This Linker
| Linker ID |
LIN0SADJZ
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| Linker Name |
WO2024105205A1-3c--9476-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C21H31N5O8
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| Isosmiles |
O=C(O)[C@@H](NC([C@H](C)N(C)C([C@H](C)NC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC(N)=O
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| InChI |
InChI=1S/C21H31N5O8/c1-12(23-16(28)7-5-4-6-10-26-17(29)8-9-18(26)30)20(32)25(3)13(2)19(31)24-14(21(33)34)11-15(22)27/h8-9,12-14H,4-7,10-11H2,1-3H3,(H2,22,27)(H,23,28)(H,24,31)(H,33,34)/t12-,13-,14-/m0/s1
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| InChIKey |
VKYPVXUQZLDAGQ-IHRRRGAJSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
481.506
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Polar area
|
196.28
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Complexity
|
808.0996224
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xlogp Value
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-1.7318
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Heavy Count
|
34
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Rot Bonds
|
14
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Hbond acc
|
7
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker