Linker Information
General Information of This Linker
| Linker ID |
LIN0RWIRG
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|---|---|---|---|---|---|---|
| Linker Name |
NZ818359A+PR300159-B81+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H43N5O4
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| Isosmiles |
CC([C@H](NC(CCCC#CC1=CN=CN=C1)=O)C(N[C@@H](CCCCN(CCC)CCC)C(O)=O)=O)C
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| InChI |
InChI=1S/C27H43N5O4/c1-5-15-32(16-6-2)17-11-10-13-23(27(35)36)30-26(34)25(21(3)4)31-24(33)14-9-7-8-12-22-18-28-20-29-19-22/h18-21,23,25H,5-7,9-11,13-17H2,1-4H3,(H,30,34)(H,31,33)(H,35,36)/t23-,25-/m0/s1
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| InChIKey |
GJVMSQUKCNKZQV-ZCYQVOJMSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
501.672
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Polar area
|
124.52
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Complexity
|
806.5894382
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xlogp Value
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3.0009
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Heavy Count
|
36
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Rot Bonds
|
17
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Hbond acc
|
6
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker