Linker Information
General Information of This Linker
| Linker ID |
LIN0RUXJA
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| Linker Name |
CN118878620A+Drug linker 11+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H41N7O8
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| Isosmiles |
O=C(N[C@@H](CCCNC(N)=O)C(O)=O)[C@@H](NC(CNC(CNC(CCC(N1C2=C(C#CC3=C(C=CC=C3)C1)C=CC=C2)=O)=O)=O)=O)C(C)C
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| InChI |
InChI=1S/C34H41N7O8/c1-21(2)31(32(46)39-25(33(47)48)11-7-17-36-34(35)49)40-29(44)19-38-28(43)18-37-27(42)15-16-30(45)41-20-24-10-4-3-8-22(24)13-14-23-9-5-6-12-26(23)41/h3-6,8-10,12,21,25,31H,7,11,15-20H2,1-2H3,(H,37,42)(H,38,43)(H,39,46)(H,40,44)(H,47,48)(H3,35,36,49)/t25-,31-/m0/s1
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| InChIKey |
WNQUMAHCFJXLSA-FKAPRUDGSA-N
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| Pharmaceutical Properties |
Molecule Weight
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675.743
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Polar area
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229.13
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Complexity
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1572.802648
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xlogp Value
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0.1043
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Heavy Count
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49
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Rot Bonds
|
16
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Hbond acc
|
7
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker