Linker Information
General Information of This Linker
| Linker ID |
LIN0RUFNE
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| Linker Name |
TW202436324A+ADC-6+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H44N4O10
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| Isosmiles |
C[C@H](NC([C@H](NC(CCOCCOCCOCCOCCN1C(C=CC1=O)=O)=O)C(C)C)=O)C(NC2=CC=C(CO)C=C2)=O
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| InChI |
InChI=1S/C30H44N4O10/c1-21(2)28(30(40)31-22(3)29(39)32-24-6-4-23(20-35)5-7-24)33-25(36)10-12-41-14-16-43-18-19-44-17-15-42-13-11-34-26(37)8-9-27(34)38/h4-9,21-22,28,35H,10-20H2,1-3H3,(H,31,40)(H,32,39)(H,33,36)/t22-,28+/m0/s1
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| InChIKey |
ACRVNBMVTYWPAO-RBISFHTESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
620.7
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Polar area
|
181.83
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Complexity
|
.
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xlogp Value
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0.1444
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Heavy Count
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44
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Rot Bonds
|
22
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Hbond acc
|
10
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker