Linker Information
General Information of This Linker
| Linker ID |
LIN0RQATF
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| Linker Name |
ADCC2-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H51N7O15S
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| Isosmiles |
O=C(NCC(NCC(N[C@H](C(NCC(O)=O)=O)CC1=CC=CC=C1)=O)=O)[C@@H](NC(CCCCCN2C(C=CC2=O)=O)=O)CCC(NC[C@@H]3[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O3)=O.[S]
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| InChI |
InChI=1S/C37H51N7O15.S/c45-20-25-34(55)35(56)33(54)24(59-25)16-38-26(46)11-10-22(42-27(47)9-5-2-6-14-44-30(50)12-13-31(44)51)36(57)40-17-28(48)39-18-29(49)43-23(37(58)41-19-32(52)53)15-21-7-3-1-4-8-21;/h1,3-4,7-8,12-13,22-25,33-35,45,54-56H,2,5-6,9-11,14-20H2,(H,38,46)(H,39,48)(H,40,57)(H,41,58)(H,42,47)(H,43,49)(H,52,53);/t22-,23-,24+,25-,33+,34-,35-;/m0./s1
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| InChIKey |
AOFMOULFSIJPQV-FKUPSLOZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
865.916
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Polar area
|
339.43
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Complexity
|
1598.298893
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xlogp Value
|
-4.4957
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Heavy Count
|
60
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Rot Bonds
|
24
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Hbond acc
|
14
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker