Linker Information
General Information of This Linker
| Linker ID |
LIN0ROPIK
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| Linker Name |
L1-P1 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H38N6O10
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| Isosmiles |
CC([C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C=C2)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C28H38N6O10/c1-17(2)24(33-21(35)11-14-43-15-13-34-22(36)9-10-23(34)37)26(39)32-20(4-3-12-30-27(29)40)25(38)31-19-7-5-18(6-8-19)16-44-28(41)42/h5-10,17,20,24H,3-4,11-16H2,1-2H3,(H,31,38)(H,32,39)(H,33,35)(H,41,42)(H3,29,30,40)/t20-,24-/m0/s1
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| InChIKey |
KRYHBPLYCIGYAZ-RDPSFJRHSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
618.644
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Polar area
|
235.56
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Complexity
|
1158.897312
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xlogp Value
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0.2255
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Heavy Count
|
44
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Rot Bonds
|
18
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker