Linker Information
General Information of This Linker
| Linker ID |
LIN0RNZTO
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| Linker Name |
CN112604004B-SCT-200-C-3-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C35H41N5O9
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| Isosmiles |
O=C(O)OCC1=CC=C(NC(CNC(C(CNC(CNC(CC2CCC(CC2)CCN3C(C=CC3=O)=O)=O)=O)C4=CC=CC=C4)=O)=O)C=C1
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| InChI |
InChI=1S/C35H41N5O9/c41-29(18-24-8-6-23(7-9-24)16-17-40-32(44)14-15-33(40)45)37-20-30(42)36-19-28(26-4-2-1-3-5-26)34(46)38-21-31(43)39-27-12-10-25(11-13-27)22-49-35(47)48/h1-5,10-15,23-24,28H,6-9,16-22H2,(H,36,42)(H,37,41)(H,38,46)(H,39,43)(H,47,48)
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| InChIKey |
BPKQOPJALWXXLX-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
675.739
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Polar area
|
200.31
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Complexity
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1462.76906
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xlogp Value
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2.4637
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Heavy Count
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49
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Rot Bonds
|
16
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Hbond acc
|
8
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker