Linker Information
General Information of This Linker
| Linker ID |
LIN0RMBFD
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| Linker Name |
Daratumumab-I-27--0.02 linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C70H115FN14O24
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| Isosmiles |
N=C(NCCC[C@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(C(NC(CCOCCOCCOCCOCCOCCOCCN)=O)CCC(OC1=CC=C(F)C=C1)=O)=O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC2=CNC3=C2C=CC=C3)C(O)=O)=O)=O)=O)N
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| InChI |
InChI=1S/C70H115FN14O24/c71-53-9-11-54(12-10-53)109-64(89)14-13-59(83-62(87)16-22-96-26-30-100-34-38-103-41-43-105-39-35-101-31-27-97-23-17-72)65(90)77-20-24-98-28-32-102-36-40-106-44-46-108-48-47-107-45-42-104-37-33-99-29-25-95-21-15-61(86)82-58(8-4-19-79-70(75)76)67(92)85-57(7-3-18-78-69(73)74)66(91)81-51-63(88)84-60(68(93)94)49-52-50-80-56-6-2-1-5-55(52)56/h1-2,5-6,9-12,50,57-60,80H,3-4,7-8,13-49,51,72H2,(H,77,90)(H,81,91)(H,82,86)(H,83,87)(H,84,88)(H,85,92)(H,93,94)(H4,73,74,78)(H4,75,76,79)/t57-,58-,59?,60-/m0/s1
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| InChIKey |
YWMCGGXWQRRKGB-UXIJXCIQSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1555.762
|
Polar area
|
533.03
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Complexity
|
2858.295541
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xlogp Value
|
-2.01066
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Heavy Count
|
109
|
Rot Bonds
|
71
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Hbond acc
|
26
|
Hbond Donor
|
15
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Each Antibody-drug Conjugate Related to This Linker