Linker Information
General Information of This Linker
| Linker ID |
LIN0RLKHL
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| Linker Name |
TW202436324A+ADC-7+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C41H66N6O15
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| Isosmiles |
CC(C)[C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(C=CC1=O)=O)=O)C(N[C@H](C(NC(C=C2)=CC=C2CO)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C41H66N6O15/c1-31(2)38(40(53)45-34(4-3-12-43-41(42)54)39(52)44-33-7-5-32(30-48)6-8-33)46-35(49)11-14-55-16-18-57-20-22-59-24-26-61-28-29-62-27-25-60-23-21-58-19-17-56-15-13-47-36(50)9-10-37(47)51/h5-10,31,34,38,48H,3-4,11-30H2,1-2H3,(H,44,52)(H,45,53)(H,46,49)(H3,42,43,54)/t34-,38+/m0/s1
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| InChIKey |
LPYRLBZQWGXQDH-HCJVMEMPSA-N
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| Pharmaceutical Properties |
Molecule Weight
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883.006
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Polar area
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273.87
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Complexity
|
1389.989643
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xlogp Value
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-0.3606
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Heavy Count
|
62
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Rot Bonds
|
38
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Hbond acc
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15
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker