Linker Information
General Information of This Linker
| Linker ID |
LIN0RLJXN
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| Linker Name |
CN119630431A-ADC-75-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C32H45N5O15
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| Isosmiles |
CN(CCNC)C(OCC1=CC=C(O[C@H](O2)[C@H](O)[C@@H](O)[C@H](O)[C@H]2C(O)=O)C(NC(CCNC(CCOCCOCCN3C(C=CC3=O)=O)=O)=O)=C1)=O
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| InChI |
InChI=1S/C32H45N5O15/c1-33-10-11-36(2)32(47)50-18-19-3-4-21(51-31-28(44)26(42)27(43)29(52-31)30(45)46)20(17-19)35-23(39)7-9-34-22(38)8-13-48-15-16-49-14-12-37-24(40)5-6-25(37)41/h3-6,17,26-29,31,33,42-44H,7-16,18H2,1-2H3,(H,34,38)(H,35,39)(H,45,46)/t26-,27-,28+,29-,31+/m0/s1
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| InChIKey |
GNCUVKUPSNRIEV-SQQOACJHSA-N
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| Pharmaceutical Properties |
Molecule Weight
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739.732
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Polar area
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272.06
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Complexity
|
1358.359864
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xlogp Value
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-2.4615
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Heavy Count
|
52
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Rot Bonds
|
21
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Hbond acc
|
15
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker