Linker Information
General Information of This Linker
| Linker ID |
LIN0RDAEI
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|---|---|---|---|---|---|---|
| Linker Name |
Conjugate No.147 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C41H66N10O24
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| Isosmiles |
O[C@@H]([C@@H](O)[C@H](O)[C@@H](O)CNC(CCC(NC(CCOCCNC(CNC(CNC(CNC(CNC([C@@H](NC(CN1C(C=CC1=O)=O)=O)CCC(O)=O)=O)=O)=O)=O)=O)=O)C(NC[C@H](O)[C@H](O)[C@H](O)[C@H](O)CO)=O)=O)CO
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| InChI |
InChI=1S/C41H66N10O24/c52-18-24(56)38(71)36(69)22(54)11-43-26(58)3-1-20(40(73)47-12-23(55)37(70)39(72)25(57)19-53)49-27(59)7-9-75-10-8-42-28(60)13-44-29(61)14-45-30(62)15-46-31(63)16-48-41(74)21(2-6-35(67)68)50-32(64)17-51-33(65)4-5-34(51)66/h4-5,20-25,36-39,52-57,69-72H,1-3,6-19H2,(H,42,60)(H,43,58)(H,44,61)(H,45,62)(H,46,63)(H,47,73)(H,48,74)(H,49,59)(H,50,64)(H,67,68)/t20?,21-,22-,23-,24+,25+,36+,37-,38+,39+/m0/s1
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| InChIKey |
ZCCULTMTZYELJT-RDDLMQGGSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1083.025
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Polar area
|
548.11
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Complexity
|
1874.860791
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xlogp Value
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-13.3821
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Heavy Count
|
75
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Rot Bonds
|
38
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Hbond acc
|
23
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Hbond Donor
|
20
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Each Antibody-drug Conjugate Related to This Linker