Linker Information
General Information of This Linker
| Linker ID |
LIN0QYPOV
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
CN119630431A-ADC-17-LINKER
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C26H34N6O9
|
|||||
| Isosmiles |
O=C(N1CCOCCOCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(N)=O)=O)=O)=O)=O)C=CC1=O
|
|||||
| InChI |
InChI=1S/C26H34N6O9/c27-20(33)15-30-26(39)19(14-18-4-2-1-3-5-18)31-23(36)17-29-22(35)16-28-21(34)8-10-40-12-13-41-11-9-32-24(37)6-7-25(32)38/h1-7,19H,8-17H2,(H2,27,33)(H,28,34)(H,29,35)(H,30,39)(H,31,36)/t19-/m0/s1
|
|||||
| InChIKey |
QXEFHRWNMGUATC-IBGZPJMESA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
574.591
|
Polar area
|
215.33
|
||
|
Complexity
|
1054.294887
|
xlogp Value
|
-3.1039
|
|||
|
Heavy Count
|
41
|
Rot Bonds
|
19
|
|||
|
Hbond acc
|
9
|
Hbond Donor
|
5
|
|||
Each Antibody-drug Conjugate Related to This Linker