Linker Information
General Information of This Linker
| Linker ID |
LIN0QWZUD
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| Linker Name |
IG-L-77 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C51H72FN13O19
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| Isosmiles |
CN(C(CN(C)C(CN(C(CN(C(CN(C)C(CN(C(CN(C)C(CN(C)C(CN(C(CN(C)C(CCCOC1=C(F)C(N2C(C=CC2=O)=O)=CC=C1CCC(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)C)=O)=O)=O)C)=O)=O)C)=O)C)=O)=O)CC(O)=O
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| InChI |
InChI=1S/C51H72FN13O19/c1-55(36(68)12-11-19-84-50-31(14-16-35(67)54-32(51(82)83)20-34(53)66)13-15-33(49(50)52)65-37(69)17-18-38(65)70)21-39(71)56(2)22-40(72)57(3)23-41(73)58(4)24-42(74)59(5)25-43(75)60(6)26-44(76)61(7)27-45(77)62(8)28-46(78)63(9)29-47(79)64(10)30-48(80)81/h13,15,17-18,32H,11-12,14,16,19-30H2,1-10H3,(H2,53,66)(H,54,67)(H,80,81)(H,82,83)/t32-/m0/s1
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| InChIKey |
RWFZUKAPYVROIU-YTTGMZPUSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1190.207
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Polar area
|
396.5
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Complexity
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2640.637733
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xlogp Value
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-5.5399
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Heavy Count
|
84
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Rot Bonds
|
33
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Hbond acc
|
17
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker