Linker Information
General Information of This Linker
| Linker ID |
LIN0QWMLF
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| Linker Name |
NH2-PEG4-vcPABC
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H50N6O11
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| Isosmiles |
CC([C@H](NC(CCOCCOCCOCCOCCN)=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(C=C1)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C30H50N6O11/c1-21(2)26(36-25(37)9-12-43-14-16-45-18-19-46-17-15-44-13-10-31)28(39)35-24(4-3-11-33-29(32)40)27(38)34-23-7-5-22(6-8-23)20-47-30(41)42/h5-8,21,24,26H,3-4,9-20,31H2,1-2H3,(H,34,38)(H,35,39)(H,36,37)(H,41,42)(H3,32,33,40)/t24-,26-/m0/s1
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| InChIKey |
GYBODWSLQAIDJW-AHWVRZQESA-N
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| Pharmaceutical Properties |
Molecule Weight
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670.761
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Polar area
|
251.89
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Complexity
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1014.622967
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xlogp Value
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0.309
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Heavy Count
|
47
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Rot Bonds
|
26
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker