Linker Information
General Information of This Linker
| Linker ID |
LIN0QVMVS
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| Linker Name |
CN110997009B ADC#40 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H36Br2N8O10
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| Isosmiles |
O=C(NCCOCCOCCC(NCC(NCC(NCC(NCC(NCC(O)=O)=O)=O)=O)=O)=O)C1=CC=C2C(N=C(C(CBr)=N2)CBr)=C1
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| InChI |
InChI=1S/C28H36Br2N8O10/c29-10-20-21(11-30)38-19-9-17(1-2-18(19)37-20)28(46)31-4-6-48-8-7-47-5-3-22(39)32-12-23(40)33-13-24(41)34-14-25(42)35-15-26(43)36-16-27(44)45/h1-2,9H,3-8,10-16H2,(H,31,46)(H,32,39)(H,33,40)(H,34,41)(H,35,42)(H,36,43)(H,44,45)
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| InChIKey |
ZWRHUDMYKVMOIO-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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804.45
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Polar area
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256.14
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Complexity
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1388.629124
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xlogp Value
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-1.7617
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Heavy Count
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48
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Rot Bonds
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22
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker