Linker Information
General Information of This Linker
| Linker ID |
LIN0QKDPC
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|---|---|---|---|---|---|---|
| Linker Name |
Mal-Val-Cit-PABC-EDA
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H56N8O9S
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| Isosmiles |
CC(C)C(NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)NCCNC(=O)CCC(C)(C)S)cc1
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| InChI |
InChI=1S/C37H56N8O9S/c1-24(2)32(44-29(47)10-6-5-7-22-45-30(48)15-16-31(45)49)34(51)43-27(9-8-19-40-35(38)52)33(50)42-26-13-11-25(12-14-26)23-54-36(53)41-21-20-39-28(46)17-18-37(3,4)55/h11-16,24,27,32,55H,5-10,17-23H2,1-4H3,(H,39,46)(H,41,53)(H,42,50)(H,43,51)(H,44,47)(H3,38,40,52)
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| InChIKey |
LPQDYLNYRGYWTP-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
788.969
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Polar area
|
247.23
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Complexity
|
55
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xlogp Value
|
2.0156
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Heavy Count
|
55
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Rot Bonds
|
24
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Hbond acc
|
10
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker
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