Linker Information
General Information of This Linker
| Linker ID |
LIN0QJMCV
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| Linker Name |
CN119630431A-ADC-50-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C62H95N5O24S2
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(NCCCC[C@H](NC(CCOCCOCCN1C(C(SC2=CC=CC=C2)=C(SC3=CC=CC=C3)C1=O)=O)=O)C(NCCC(N[C@H](C(O)=O)CC(O)=O)=O)=O)=O
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| InChI |
InChI=1S/C62H95N5O24S2/c1-78-24-25-82-30-31-84-34-35-86-38-39-88-42-43-90-46-47-91-45-44-89-41-40-87-37-36-85-33-32-83-29-27-79-21-16-53(68)63-18-9-8-14-51(59(73)64-19-15-54(69)66-52(62(76)77)48-56(71)72)65-55(70)17-22-80-26-28-81-23-20-67-60(74)57(92-49-10-4-2-5-11-49)58(61(67)75)93-50-12-6-3-7-13-50/h2-7,10-13,51-52H,8-9,14-48H2,1H3,(H,63,68)(H,64,73)(H,65,70)(H,66,69)(H,71,72)(H,76,77)/t51-,52-/m0/s1
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| InChIKey |
XTAWQSVOJJXQFV-XWQGWOARSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1358.587
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Polar area
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357.6
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Complexity
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2226.166089
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xlogp Value
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2.1155
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Heavy Count
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93
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Rot Bonds
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63
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Hbond acc
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24
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker