Linker Information
General Information of This Linker
| Linker ID |
LIN0QHPLI
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| Linker Name |
Mc-Val-Glu-RG-1
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C35H42N6O11
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| Isosmiles |
O=C(N[C@@H](CCC(O)=O)C(NC1=CC=C(COC(NCC2=CC=CC=C2N(C)C(O)=O)=O)C=C1)=O)[C@H](C)NC(CCCCCN3C(C=CC3=O)=O)=O
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| InChI |
InChI=1S/C35H42N6O11/c1-22(37-28(42)10-4-3-7-19-41-29(43)16-17-30(41)44)32(47)39-26(15-18-31(45)46)33(48)38-25-13-11-23(12-14-25)21-52-34(49)36-20-24-8-5-6-9-27(24)40(2)35(50)51/h5-6,8-9,11-14,16-17,22,26H,3-4,7,10,15,18-21H2,1-2H3,(H,36,49)(H,37,42)(H,38,48)(H,39,47)(H,45,46)(H,50,51)/t22-,26-/m0/s1
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| InChIKey |
DWESKZFBLLFMDX-NVQXNPDNSA-N
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| Pharmaceutical Properties |
Molecule Weight
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722.752
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Polar area
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240.85
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Complexity
|
1595.986439
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xlogp Value
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2.5054
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Heavy Count
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52
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Rot Bonds
|
19
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker