Linker Information
General Information of This Linker
| Linker ID |
LIN0QFEOD
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| Linker Name |
Mal-PEG2-Val-Cit-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H42N6O9
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| Isosmiles |
CC(C)[C@H](NC(CCOCCOCCN1C(C=CC1=O)=O)=O)C(N[C@H](C(NC2=CC=C(CO)C=C2)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C29H42N6O9/c1-19(2)26(34-23(37)11-14-43-16-17-44-15-13-35-24(38)9-10-25(35)39)28(41)33-22(4-3-12-31-29(30)42)27(40)32-21-7-5-20(18-36)6-8-21/h5-10,19,22,26,36H,3-4,11-18H2,1-2H3,(H,32,40)(H,33,41)(H,34,37)(H3,30,31,42)/t22-,26-/m0/s1
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| InChIKey |
NXGJAGHMGZCZSF-NVQXNPDNSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
618.688
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Polar area
|
218.49
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Complexity
|
1099.074443
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xlogp Value
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-0.4602
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Heavy Count
|
44
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Rot Bonds
|
20
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker