Linker Information
General Information of This Linker
| Linker ID |
LIN0QEHZQ
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|---|---|---|---|---|---|---|
| Linker Name |
Linker145
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H45N9O9
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| Isosmiles |
[H][C@@]12CCC(N=NN3)=C3CC[C@]1([H])[C@@H]2COC(O)=O.[H][C@@]45CCC(N=NN6)=C6CC[C@]4([H])[C@@H]5COC(O)=O.[H][C@]78CCC9=C(N=NN9)CC[C@@]7([H])[C@H]8COC(O)=O
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| InChI |
InChI=1S/3C11H15N3O3/c3*15-11(16)17-5-8-6-1-3-9-10(13-14-12-9)4-2-7(6)8/h3*6-8H,1-5H2,(H,15,16)(H,12,13,14)/t3*6-,7+,8-
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| InChIKey |
BGKGRXRZMPKISL-GXWRQHJTSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
711.777
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Polar area
|
264.3
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Complexity
|
1333.573052
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xlogp Value
|
3.7209
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Heavy Count
|
51
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Rot Bonds
|
6
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Hbond acc
|
12
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker