Linker Information
General Information of This Linker
| Linker ID |
LIN0QEDQN
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| Linker Name |
Phenoxy silyl linker 36
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| Linker Type |
Reduction sensitive linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H56N6O12S2Si
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| Isosmiles |
CC([Si](OC1=CC=C(CO)C=C1)(OCCOCC(N=N2)=CN2CCOCCOCCOCCNC(C3=CC(NS(C=C)(=O)=O)=CC(NS(C=C)(=O)=O)=C3)=O)C(C)C)C
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| InChI |
InChI=1S/C37H56N6O12S2Si/c1-7-56(46,47)40-33-23-32(24-34(25-33)41-57(48,49)8-2)37(45)38-13-15-50-17-19-52-20-18-51-16-14-43-26-35(39-42-43)28-53-21-22-54-58(29(3)4,30(5)6)55-36-11-9-31(27-44)10-12-36/h7-12,23-26,29-30,40-41,44H,1-2,13-22,27-28H2,3-6H3,(H,38,45)
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| InChIKey |
ONYYBZPHILSUIJ-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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869.105
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Polar area
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227.76
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Complexity
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1809.405257
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xlogp Value
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3.895
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Heavy Count
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58
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Rot Bonds
|
30
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Hbond acc
|
15
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker