Linker Information
General Information of This Linker
| Linker ID |
LIN0PYRYS
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| Linker Name |
MT-VC-PABC
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C31H46N6O10
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| Isosmiles |
CC([C@H](NC(CCOCCOCCOCCN1C(C=CC1=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(CO)C=C2)=O)=O)C
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| PubChem CID | ||||||
| InChI |
InChI=1S/C31H46N6O10/c1-21(2)28(36-25(39)11-14-45-16-18-47-19-17-46-15-13-37-26(40)9-10-27(37)41)30(43)35-24(4-3-12-33-31(32)44)29(42)34-23-7-5-22(20-38)6-8-23/h5-10,21,24,28,38H,3-4,11-20H2,1-2H3,(H,34,42)(H,35,43)(H,36,39)(H3,32,33,44)/t24-,28-/m0/s1
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| InChIKey |
VHEYULNIIMAPFL-CUBQBAPOSA-N
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| Pharmaceutical Properties |
Molecule Weight
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662.741
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Polar area
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227.72
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Complexity
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1146.895094
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xlogp Value
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-0.4436
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Heavy Count
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47
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Rot Bonds
|
23
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Hbond acc
|
10
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker