Linker Information
General Information of This Linker
| Linker ID |
LIN0PYORI
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|---|---|---|---|---|---|---|
| Linker Name |
CN113549127A-ADC-22-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C38H64N6O14S
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| Isosmiles |
NCCCC[C@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC#CC1=CN=C(S)N=C1)=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C38H64N6O14S/c39-9-5-4-7-33(37(48)49)44-36(47)31-58-30-35(46)41-11-13-51-15-17-53-19-21-55-23-25-57-27-26-56-24-22-54-20-18-52-16-14-50-12-10-40-34(45)8-3-1-2-6-32-28-42-38(59)43-29-32/h28-29,33H,1,3-5,7-27,30-31,39H2,(H,40,45)(H,41,46)(H,44,47)(H,48,49)(H,42,43,59)/t33-/m0/s1
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| InChIKey |
BQQXECPYSAUCEH-XIFFEERXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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861.025
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Polar area
|
259.47
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Complexity
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1212.728127
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xlogp Value
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-0.6327
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Heavy Count
|
59
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Rot Bonds
|
40
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Hbond acc
|
17
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker