Linker Information
General Information of This Linker
| Linker ID |
LIN0PWVSZ
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| Linker Name |
TW202436324A+ADC-2+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H34N4O6
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| Isosmiles |
C[C@H](NC([C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(C)C)=O)C(NC2=CC=C(CO)C=C2)=O
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| InChI |
InChI=1S/C25H34N4O6/c1-16(2)23(28-20(31)7-5-4-6-14-29-21(32)12-13-22(29)33)25(35)26-17(3)24(34)27-19-10-8-18(15-30)9-11-19/h8-13,16-17,23,30H,4-7,14-15H2,1-3H3,(H,26,35)(H,27,34)(H,28,31)/t17-,23+/m0/s1
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| InChIKey |
DAMSURYLURICHN-GAJHUEQPSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
486.569
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Polar area
|
144.91
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Complexity
|
899.2899266
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xlogp Value
|
1.2483
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Heavy Count
|
35
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Rot Bonds
|
13
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Hbond acc
|
6
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker