Linker Information
General Information of This Linker
| Linker ID |
LIN0PTZPY
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|---|---|---|---|---|---|---|
| Linker Name |
CHH0191, 13i-5657, Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C15H22N2O8
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| Isosmiles |
O=C(O)CCOCCOCCOCCNC(CN1C(C=CC1=O)=O)=O
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| InChI |
InChI=1S/C15H22N2O8/c18-12(11-17-13(19)1-2-14(17)20)16-4-6-24-8-10-25-9-7-23-5-3-15(21)22/h1-2H,3-11H2,(H,16,18)(H,21,22)
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| InChIKey |
BSZDDLQKLBVTLU-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
358.347
|
Polar area
|
131.47
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Complexity
|
456.2667787
|
xlogp Value
|
-1.4479
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Heavy Count
|
25
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Rot Bonds
|
14
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Hbond acc
|
7
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker