Linker Information
General Information of This Linker
| Linker ID |
LIN0PMDJV
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| Linker Name |
TW202506738A-C-123-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H56N6O15
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| Isosmiles |
CC1=CC=C(NC([C@@H](NC(CCCNC([C@H](CCC(NCCOCOCOCOCOCOCOCOC)=O)NC(CCCN2C(C=CC2=O)=O)=O)=O)=O)C)=O)C=C1
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| InChI |
InChI=1S/C37H56N6O15/c1-27-8-10-29(11-9-27)41-36(49)28(2)40-32(45)6-4-16-39-37(50)30(42-33(46)7-5-18-43-34(47)14-15-35(43)48)12-13-31(44)38-17-19-52-21-54-23-56-25-58-26-57-24-55-22-53-20-51-3/h8-11,14-15,28,30H,4-7,12-13,16-26H2,1-3H3,(H,38,44)(H,39,50)(H,40,45)(H,41,49)(H,42,46)/t28-,30-/m0/s1
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| InChIKey |
JFEMUVMSVRGONX-JDXGNMNLSA-N
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| Pharmaceutical Properties |
Molecule Weight
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824.882
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Polar area
|
256.72
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Complexity
|
1371.587817
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xlogp Value
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-0.11388
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Heavy Count
|
58
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Rot Bonds
|
33
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Hbond acc
|
15
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker