Linker Information
General Information of This Linker
| Linker ID |
LIN0PIFFL
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| Linker Name |
Anti-Her2-AL1- LP4 LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H51N9O10
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| Isosmiles |
O=C(N1C(N=NN2CCOCCOCCOCCN)=C2CCCCC1)CCC(NCC(NCC(N[C@@H](CC3=CC=CC=C3)C(NCC(O)=O)=O)=O)=O)=O
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| InChI |
InChI=1S/C34H51N9O10/c35-12-15-51-17-19-53-20-18-52-16-14-43-27-9-5-2-6-13-42(33(27)40-41-43)31(47)11-10-28(44)36-22-29(45)37-23-30(46)39-26(34(50)38-24-32(48)49)21-25-7-3-1-4-8-25/h1,3-4,7-8,26H,2,5-6,9-24,35H2,(H,36,44)(H,37,45)(H,38,50)(H,39,46)(H,48,49)/t26-/m0/s1
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| InChIKey |
VKJLUGUUNPWSGH-SANMLTNESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
745.835
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Polar area
|
258.43
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Complexity
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1405.023506
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xlogp Value
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-1.7131
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Heavy Count
|
53
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Rot Bonds
|
24
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Hbond acc
|
13
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker