Linker Information
General Information of This Linker
| Linker ID |
LIN0PEKWS
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| Linker Name |
CN113549127A-ADC-27-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C22H34N4O7S2
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| Isosmiles |
CC(C)[C@H](NC(CCCCCN1C(C(S)=C(S)C1=O)=O)=O)C(N[C@H](C(O)=O)CCCCC(N)=O)=O
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| InChI |
InChI=1S/C22H34N4O7S2/c1-12(2)16(19(29)24-13(22(32)33)8-5-6-9-14(23)27)25-15(28)10-4-3-7-11-26-20(30)17(34)18(35)21(26)31/h12-13,16,34-35H,3-11H2,1-2H3,(H2,23,27)(H,24,29)(H,25,28)(H,32,33)/t13-,16-/m0/s1
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| InChIKey |
UEYLLNITIYDQFW-BBRMVZONSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
530.669
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Polar area
|
175.97
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Complexity
|
800.0996224
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xlogp Value
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0.7427
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Heavy Count
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35
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Rot Bonds
|
16
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker