Linker Information
General Information of This Linker
| Linker ID |
LIN0PCDVL
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|---|---|---|---|---|---|---|
| Linker Name |
WO2023173026A1-ADC-L081-036-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H42N4O8
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| Isosmiles |
OC(CCOCCOCCOCCOCCNC([C@H](CCCCC)NC(C1=CC=C(N)C(N)=C1)=O)=O)=O
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| InChI |
InChI=1S/C25H42N4O8/c1-2-3-4-5-22(29-24(32)19-6-7-20(26)21(27)18-19)25(33)28-9-11-35-13-15-37-17-16-36-14-12-34-10-8-23(30)31/h6-7,18,22H,2-5,8-17,26-27H2,1H3,(H,28,33)(H,29,32)(H,30,31)/t22-/m0/s1
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| InChIKey |
QKPCQXFXDMHYKM-QFIPXVFZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
526.631
|
Polar area
|
184.46
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Complexity
|
764.2430314
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xlogp Value
|
1.187
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Heavy Count
|
37
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Rot Bonds
|
22
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Hbond acc
|
9
|
Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker