Linker Information
General Information of This Linker
| Linker ID |
LIN0PALKX
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| Linker Name |
WO2024105205A1-12m-170a-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C16H23N3O6
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| Isosmiles |
OC([C@@H](C)NC([C@H](C)NC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O
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| InChI |
InChI=1S/C16H23N3O6/c1-10(15(23)18-11(2)16(24)25)17-12(20)6-4-3-5-9-19-13(21)7-8-14(19)22/h7-8,10-11H,3-6,9H2,1-2H3,(H,17,20)(H,18,23)(H,24,25)/t10-,11+/m0/s1
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| InChIKey |
VFRYCQJIMHOXCB-WDEREUQCSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
353.375
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Polar area
|
132.88
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Complexity
|
536.5873849
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xlogp Value
|
-0.4342
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Heavy Count
|
25
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Rot Bonds
|
10
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Hbond acc
|
5
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker