Linker Information
General Information of This Linker
| Linker ID |
LIN0OWUQP
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| Linker Name |
TW202506738A-C-353-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C70H118N10O31
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCC(NCCCC[C@H](NC(CNC(CCCNC([C@H](NC(CCN1C(C=CC1=O)=O)=O)[C@@H](NC(CCN2C(C=CC2=O)=O)=O)C(NCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)=O)C(NCCCC(O)=O)=O)=O
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| InChI |
InChI=1S/C70H118N10O31/c1-95-23-25-98-29-31-101-35-37-104-41-43-106-40-39-103-34-33-100-28-27-97-22-19-74-70(94)67(78-58(83)15-21-80-63(88)12-13-64(80)89)66(77-57(82)14-20-79-61(86)10-11-62(79)87)69(93)73-17-5-8-56(81)75-53-59(84)76-55(68(92)72-18-6-9-65(90)91)7-3-4-16-71-60(85)54-111-52-51-110-50-49-109-48-47-108-46-45-107-44-42-105-38-36-102-32-30-99-26-24-96-2/h10-13,55,66-67H,3-9,14-54H2,1-2H3,(H,71,85)(H,72,92)(H,73,93)(H,74,94)(H,75,81)(H,76,84)(H,77,82)(H,78,83)(H,90,91)/t55-,66+,67+/m0/s1
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| InChIKey |
BMDXYXITLLAHKL-NWCBOLORSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1595.753
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Polar area
|
501.77
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Complexity
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2529.71993
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xlogp Value
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-4.9909
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Heavy Count
|
111
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Rot Bonds
|
78
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Hbond acc
|
30
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker